Total Neoadjuvant Therapy With FOLFIRINOX Followed by Individualized Chemoradiotherapy for Borderline Resectable Pancreatic Adenocarcinoma: A Phase 2 Clinical Trial

IMPORTANCE: Patients with borderline-resectable pancreatic ductal adenocarcinoma have historically poor outcomes with surgery followed by adjuvant chemotherapy. Evaluation of a total neoadjuvant approach with highly active therapy is warranted. OBJECTIVE: To evaluate the margin-negative (R0) resecti...

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Detalhes bibliográficos
Publicado no:JAMA Oncol
Main Authors: Murphy, Janet E., Wo, Jennifer Y., Ryan, David P., Jiang, Wenqing, Yeap, Beow Y., Drapek, Lorraine C., Blaszkowsky, Lawrence S., Kwak, Eunice L., Allen, Jill N., Clark, Jeffrey W., Faris, Jason E., Zhu, Andrew X., Goyal, Lipika, Lillemoe, Keith D., DeLaney, Thomas F., Fernández-del Castillo, Carlos, Ferrone, Cristina R., Hong, Theodore S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2018
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6145728/
https://ncbi.nlm.nih.gov/pubmed/29800971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2018.0329
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