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Pharmacological inhibition of LSD1 activity blocks REST-dependent medulloblastoma cell migration
BACKGROUND: Medulloblastoma (MB) is the most common malignant brain tumor in children. Current problems in the clinic include metastasis, recurrence, and treatment-related sequelae that highlight the need for targeted therapies. Epigenetic perturbations are an established hallmark of human MB and ex...
Gespeichert in:
| Veröffentlicht in: | Cell Commun Signal |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6145331/ https://ncbi.nlm.nih.gov/pubmed/30227871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-018-0275-5 |
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