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Pharmacological inhibition of LSD1 activity blocks REST-dependent medulloblastoma cell migration

BACKGROUND: Medulloblastoma (MB) is the most common malignant brain tumor in children. Current problems in the clinic include metastasis, recurrence, and treatment-related sequelae that highlight the need for targeted therapies. Epigenetic perturbations are an established hallmark of human MB and ex...

詳細記述

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書誌詳細
出版年:Cell Commun Signal
主要な著者: Callegari, Keri, Maegawa, Shinji, Bravo-Alegria, Javiera, Gopalakrishnan, Vidya
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6145331/
https://ncbi.nlm.nih.gov/pubmed/30227871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-018-0275-5
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