Inhibition of the Human ABC Efflux Transporters P-gp and BCRP by the BDE-47 Hydroxylated Metabolite 6-OH-BDE-47: Considerations for Human Exposure

High body burdens of polybrominated diphenyl ethers (PBDEs) in infants and young children have led to increased concern over their potential impact on human development. PBDE exposure can alter the expression of genes involved in thyroid homeostasis, including those of ATP-binding cassette (ABC) tra...

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Библиографические подробности
Опубликовано в: :Toxicol Sci
Главные авторы: Marchitti, Satori A., Mazur, Christopher S., Dillingham, Caleb, Rawat, Swati, Sharma, Anshika, Zastre, Jason, Kenneke, John F.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6145076/
https://ncbi.nlm.nih.gov/pubmed/28031414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw209
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