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High-throughput inference of pairwise coalescence times identifies signals of selection and enriched disease heritability

Interest in reconstructing demographic histories has motivated the development of methods to estimate locus-specific pairwise coalescence times from whole-genome sequence data. Here we introduce a powerful new method, ASMC, that can estimate coalescence times using only SNP array data, and is orders...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Palamara, Pier Francesco, Terhorst, Jonathan, Song, Yun S., Price, Alkes L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6145075/
https://ncbi.nlm.nih.gov/pubmed/30104759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-018-0177-x
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