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Argonaute-based programmable RNase as a tool for cleavage of highly-structured RNA

The recent identification and development of RNA-guided enzymes for programmable cleavage of target nucleic acids offers exciting possibilities for both therapeutic and biotechnological applications. However, critical challenges such as expensive guide RNAs and inability to predict the efficiency of...

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Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Dayeh, Daniel M, Cantara, William A, Kitzrow, Jonathan P, Musier-Forsyth, Karin, Nakanishi, Kotaro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144825/
https://ncbi.nlm.nih.gov/pubmed/29897478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky496
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