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Argonaute-based programmable RNase as a tool for cleavage of highly-structured RNA

The recent identification and development of RNA-guided enzymes for programmable cleavage of target nucleic acids offers exciting possibilities for both therapeutic and biotechnological applications. However, critical challenges such as expensive guide RNAs and inability to predict the efficiency of...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Dayeh, Daniel M, Cantara, William A, Kitzrow, Jonathan P, Musier-Forsyth, Karin, Nakanishi, Kotaro
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144825/
https://ncbi.nlm.nih.gov/pubmed/29897478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky496
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