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Characterizing the 3D structure and dynamics of chromosomes and proteins in a common contact matrix framework

Conformational ensembles of biopolymers, whether proteins or chromosomes, can be described using contact matrices. Principal component analysis (PCA) on the contact data has been used to interrogate both protein and chromosome structures and/or dynamics. However, as these fields have developed separ...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Lindsay, Richard J, Pham, Bill, Shen, Tongye, McCord, Rachel Patton
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144818/
https://ncbi.nlm.nih.gov/pubmed/29992238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky604
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