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Characterizing the 3D structure and dynamics of chromosomes and proteins in a common contact matrix framework

Conformational ensembles of biopolymers, whether proteins or chromosomes, can be described using contact matrices. Principal component analysis (PCA) on the contact data has been used to interrogate both protein and chromosome structures and/or dynamics. However, as these fields have developed separ...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Lindsay, Richard J, Pham, Bill, Shen, Tongye, McCord, Rachel Patton
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144818/
https://ncbi.nlm.nih.gov/pubmed/29992238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky604
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