P04.51 TERT promoter mutation-driven TERT activation is mediated by ETS1 in BRAF V600E mutated glioma

BACKGROUND: Malignancies of the central nervous system are characterized by the highest lethality among pediatric tumors. Interestingly, brain tumors such as pleomorphic xanthoastrocytoma or epithelioid glioblastoma often harbor genomic BRAF alterations (e.g. V600E) leading to hyperactivation of the...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Gabler, L, Gojo, J, Lötsch, D, Kirchhofer, D, van Schoonhoven, S, Stojanovic, M, Schmidt, H M, Ensle, D, Czech, T, Haberler, C, Slavc, I, Spiegl-Kreinecker, S, Berger, W
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Poster Presentations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144662/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy139.285
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