P04.51 TERT promoter mutation-driven TERT activation is mediated by ETS1 in BRAF V600E mutated glioma

BACKGROUND: Malignancies of the central nervous system are characterized by the highest lethality among pediatric tumors. Interestingly, brain tumors such as pleomorphic xanthoastrocytoma or epithelioid glioblastoma often harbor genomic BRAF alterations (e.g. V600E) leading to hyperactivation of the...

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Bibliografski detalji
Izdano u:Neuro Oncol
Glavni autori: Gabler, L, Gojo, J, Lötsch, D, Kirchhofer, D, van Schoonhoven, S, Stojanovic, M, Schmidt, H M, Ensle, D, Czech, T, Haberler, C, Slavc, I, Spiegl-Kreinecker, S, Berger, W
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Poster Presentations
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144662/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy139.285
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