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P04.51 TERT promoter mutation-driven TERT activation is mediated by ETS1 in BRAF V600E mutated glioma
BACKGROUND: Malignancies of the central nervous system are characterized by the highest lethality among pediatric tumors. Interestingly, brain tumors such as pleomorphic xanthoastrocytoma or epithelioid glioblastoma often harbor genomic BRAF alterations (e.g. V600E) leading to hyperactivation of the...
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| Pubblicato in: | Neuro Oncol |
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| Autori principali: | , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6144662/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy139.285 |
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