P04.51 TERT promoter mutation-driven TERT activation is mediated by ETS1 in BRAF V600E mutated glioma

BACKGROUND: Malignancies of the central nervous system are characterized by the highest lethality among pediatric tumors. Interestingly, brain tumors such as pleomorphic xanthoastrocytoma or epithelioid glioblastoma often harbor genomic BRAF alterations (e.g. V600E) leading to hyperactivation of the...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Neuro Oncol
Huvudupphovsmän: Gabler, L, Gojo, J, Lötsch, D, Kirchhofer, D, van Schoonhoven, S, Stojanovic, M, Schmidt, H M, Ensle, D, Czech, T, Haberler, C, Slavc, I, Spiegl-Kreinecker, S, Berger, W
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2018
Ämnen:
Poster Presentations
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144662/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy139.285
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk