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P04.42 Utilising whole transcriptome profiling to increase understanding of mechanisms driving IDH-mutant glioma progression and recurrence

BACKGROUND: Gliomas are the most common primary brain tumours in adults. IDH-mutated low-grade gliomas of astrocytic lineage (astrocytomas) have a relatively indolent clinical course; however, over time they progress to a higher grade. Molecular studies revealed recurrent tumours harbour more mutati...

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Publicat a:Neuro Oncol
Autors principals: Cho, A, Hudson, A L, Colvin, E K, Hayes, S A, Wheeler, H R, Howell, V M
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144563/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy139.276
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