P01.150 hypermutations in glioblastoma are associated with increased response to immunotherapy

BACKGROUND: Glioblastomas (GBM) exhibit a hyper mutable phenotype only in a restricted subset harboring somatic or germinal mutations of mismatch-repair (MMR) genes. Immunotherapy (IT), including dendritic cell (DC) vaccination and inhibition of immune checkpoints, are actively pursued in GBM patien...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Main Authors: Anghileri, E, Zhao, J, Eoli, M, Langella, T, Pollo, B, Indraccolo, S, Pellegatta, S, Iavarone, A, Rabadan, R, Finocchiaro, G
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Poster Presentations
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144313/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy139.192
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