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P01.150 hypermutations in glioblastoma are associated with increased response to immunotherapy
BACKGROUND: Glioblastomas (GBM) exhibit a hyper mutable phenotype only in a restricted subset harboring somatic or germinal mutations of mismatch-repair (MMR) genes. Immunotherapy (IT), including dendritic cell (DC) vaccination and inhibition of immune checkpoints, are actively pursued in GBM patien...
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Publicado no: | Neuro Oncol |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6144313/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy139.192 |
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