miR-17-3p Downregulates Mitochondrial Antioxidant Enzymes and Enhances the Radiosensitivity of Prostate Cancer Cells

Radioresistance remains to be a major obstacle in the management of patients with advanced prostate cancer (PCa). We have identified a mature miR-17-3p processed from the 3′ arm of precursor miR-17, which appeared to be able to inhibit three major antioxidant enzymes located in mitochondria, i.e., m...

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Foilsithe in:Mol Ther Nucleic Acids
Main Authors: Xu, Zhi, Zhang, Yanyan, Ding, Jiaji, Hu, Weizi, Tan, Chunli, Wang, Mei, Tang, Jinhai, Xu, Yong
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Gene & Cell Therapy 2018
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143750/
https://ncbi.nlm.nih.gov/pubmed/30240971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.08.009
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