ICAM-1-LFA-1 Dependent CD8+ T-Lymphocyte Aggregation in Tumor Tissue Prevents Recirculation to Draining Lymph Nodes

The quantity of T-lymphocytes reaching the draining lymph nodes from tumors is likely important to mount effective distant responses and for the establishment of long term systemic memory. Looking into mechanisms behind lymphocyte egress, we directed our attention to leukocyte adhesion mechanisms in...

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Bibliografische gegevens
Gepubliceerd in:Front Immunol
Hoofdauteurs: Yanguas, Alba, Garasa, Saray, Teijeira, Álvaro, Aubá, Cristina, Melero, Ignacio, Rouzaut, Ana
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2018
Onderwerpen:
Immunology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143661/
https://ncbi.nlm.nih.gov/pubmed/30258446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02084
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