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Force Spectroscopy of LFA-1 and Its Ligands, ICAM-1 and ICAM-2

Single-molecule measurements of the interaction of leukocyte function-associated antigen-1 (LFA-1), expressed on Jurkat T cells, with intercellular adhesion molecules-1 and -2 (ICAM-1 and ICAM-2) were conducted using atomic force microscopy (AFM). The force spectra (i.e., unbinding force versus load...

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Bibliographische Detailangaben
Hauptverfasser: Wojcikiewicz, Ewa P., Abdulreda, Midhat H., Zhang, Xiaohui, Moy, Vincent T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570329/
https://ncbi.nlm.nih.gov/pubmed/17096550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm060559c
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