Synthesis, oligonucleotide incorporation and fluorescence properties in DNA of a bicyclic thymine analogue

Fluorescent base analogues (FBAs) have emerged as a powerful class of molecular reporters of location and environment for nucleic acids. In our overall mission to develop bright and useful FBAs for all natural nucleobases, herein we describe the synthesis and thorough characterization of bicyclic th...

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Publicado en:Sci Rep
Autores principales: Lawson, Christopher P., Füchtbauer, Anders F., Wranne, Moa S., Giraud, Tristan, Floyd, Thomas, Dumat, Blaise, Andersen, Nicolai K., H. El-Sagheer, Afaf, Brown, Tom, Gradén, Henrik, Wilhelmsson, L. Marcus, Grøtli, Morten
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143597/
https://ncbi.nlm.nih.gov/pubmed/30228309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31897-2
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