Synthesis, oligonucleotide incorporation and fluorescence properties in DNA of a bicyclic thymine analogue

Fluorescent base analogues (FBAs) have emerged as a powerful class of molecular reporters of location and environment for nucleic acids. In our overall mission to develop bright and useful FBAs for all natural nucleobases, herein we describe the synthesis and thorough characterization of bicyclic th...

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Publicat a:Sci Rep
Autors principals: Lawson, Christopher P., Füchtbauer, Anders F., Wranne, Moa S., Giraud, Tristan, Floyd, Thomas, Dumat, Blaise, Andersen, Nicolai K., H. El-Sagheer, Afaf, Brown, Tom, Gradén, Henrik, Wilhelmsson, L. Marcus, Grøtli, Morten
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143597/
https://ncbi.nlm.nih.gov/pubmed/30228309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31897-2
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