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Development of a novel UHPLC-MS/MS-based platform to quantify amines, amino acids and methylarginines for applications in human disease phenotyping

Amine quantification is an important strategy in patient stratification and personalised medicine. This is because amines, including amino acids and methylarginines impact on many homeostatic processes. One important pathway regulated by amine levels is nitric oxide synthase (NOS). NOS is regulated...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Ahmetaj-Shala, Blerina, Olanipekun, Michael, Tesfai, Abel, MacCallum, Niall, Kirkby, Nicholas S., Quinlan, Gregory J., Shih, Chih-Chin, Kawai, Ryota, Mumby, Sharon, Paul-Clark, Mark, Want, Elizabeth J., Mitchell, Jane A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143519/
https://ncbi.nlm.nih.gov/pubmed/30228360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31055-8
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