Development of a novel UHPLC-MS/MS-based platform to quantify amines, amino acids and methylarginines for applications in human disease phenotyping

Amine quantification is an important strategy in patient stratification and personalised medicine. This is because amines, including amino acids and methylarginines impact on many homeostatic processes. One important pathway regulated by amine levels is nitric oxide synthase (NOS). NOS is regulated...

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Published in:Sci Rep
Main Authors: Ahmetaj-Shala, Blerina, Olanipekun, Michael, Tesfai, Abel, MacCallum, Niall, Kirkby, Nicholas S., Quinlan, Gregory J., Shih, Chih-Chin, Kawai, Ryota, Mumby, Sharon, Paul-Clark, Mark, Want, Elizabeth J., Mitchell, Jane A.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143519/
https://ncbi.nlm.nih.gov/pubmed/30228360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31055-8
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