HMGB1: A Common Biomarker and Potential Target for TBI, Neuroinflammation, Epilepsy, and Cognitive Dysfunction

High mobility group box protein 1 (HMGB1) is a ubiquitous nuclear protein released by glia and neurons upon inflammasome activation and activates receptor for advanced glycation end products (RAGE) and toll-like receptor (TLR) 4 on the target cells. HMGB1/TLR4 axis is a key initiator of neuroinflamm...

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書目詳細資料
發表在:Front Neurosci
Main Authors: Paudel, Yam Nath, Shaikh, Mohd. Farooq, Chakraborti, Ayanabha, Kumari, Yatinesh, Aledo-Serrano, Ángel, Aleksovska, Katina, Alvim, Marina Koutsodontis Machado, Othman, Iekhsan
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2018
主題:
Neuroscience
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142787/
https://ncbi.nlm.nih.gov/pubmed/30271319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00628
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