Impact of HMGB1, RAGE, and TLR4 in Alzheimer’s Disease (AD): From Risk Factors to Therapeutic Targeting

Alzheimer’s disease (AD) is a devastating neurodegenerative disorder and a leading cause of dementia, with accumulation of amyloid-beta (Aβ) and neurofibrillary tangles (NFTs) as defining pathological features. AD presents a serious global health concern with no cure to date, reflecting the complexi...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Paudel, Yam Nath, Angelopoulou, Efthalia, Piperi, Christina, Othman, Iekhsan, Aamir, Khurram, Shaikh, Mohd. Farooq
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072620/
https://ncbi.nlm.nih.gov/pubmed/32046119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020383
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