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The mutational landscape of chronic lymphocytic leukemia and its impact on prognosis and treatment

The typical genome of chronic lymphocytic leukemia (CLL) carries ∼2000 molecular lesions. Few mutations recur across patients at a frequency >5%, whereas a large number of biologically and clinically uncharacterized genes are mutated at lower frequency. Approximately 80% of CLL patients carry at...

詳細記述

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書誌詳細
出版年:Hematology Am Soc Hematol Educ Program
主要な著者: Gaidano, Gianluca, Rossi, Davide
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142556/
https://ncbi.nlm.nih.gov/pubmed/29222275
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