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The mutational landscape of chronic lymphocytic leukemia and its impact on prognosis and treatment
The typical genome of chronic lymphocytic leukemia (CLL) carries ∼2000 molecular lesions. Few mutations recur across patients at a frequency >5%, whereas a large number of biologically and clinically uncharacterized genes are mutated at lower frequency. Approximately 80% of CLL patients carry at...
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| Publicado no: | Hematology Am Soc Hematol Educ Program |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6142556/ https://ncbi.nlm.nih.gov/pubmed/29222275 |
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