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The mutational landscape of chronic lymphocytic leukemia and its impact on prognosis and treatment
The typical genome of chronic lymphocytic leukemia (CLL) carries ∼2000 molecular lesions. Few mutations recur across patients at a frequency >5%, whereas a large number of biologically and clinically uncharacterized genes are mutated at lower frequency. Approximately 80% of CLL patients carry at...
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| 出版年: | Hematology Am Soc Hematol Educ Program |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6142556/ https://ncbi.nlm.nih.gov/pubmed/29222275 |
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