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What is the role of an extended half-life product in immune tolerance induction in a patient with severe hemophilia A and high-titer inhibitors?

A 10-year-old boy presents with a history of severe hemophilia A and high-titer inhibitor that had failed high-dose immune tolerance induction (ITI) with a recombinant factor VIII (rFVIII) product and a plasma-derived FVIII product. You are asked by his mother whether he should be tried on ITI with...

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Vydáno v:Hematology Am Soc Hematol Educ Program
Hlavní autoři: Janbain, Maissaa, Pipe, Steven
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142440/
https://ncbi.nlm.nih.gov/pubmed/27913541
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