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Glutamatergic Deficits in Schizophrenia – Biomarkers and Pharmacological Interventions within the Ketamine Model

BACKGROUND: The observation that N-methyl-D-aspartate glutamate receptor (NMDAR) antagonists such as ketamine transiently induce schizophrenia-like positive, negative and cognitive symptoms has led to a paradigm shift from dopaminergic to glutamatergic dysfunction in pharmacological models of schizo...

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Podrobná bibliografie
Vydáno v:Curr Pharm Biotechnol
Hlavní autoři: Haaf, Moritz, Leicht, Gregor, Curic, Stjepan, Mulert, Christoph
Médium: Artigo
Jazyk:Inglês
Vydáno: Bentham Science Publishers 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142413/
https://ncbi.nlm.nih.gov/pubmed/29929462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1389201019666180620112528
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