HIV-1 gag recruits PACSIN2 to promote virus spreading

The p2b domain of Rous sarcoma virus (RSV) Gag and the p6 domain of HIV-1 Gag contain late assembly (L) domains that engage the ESCRT membrane fission machinery and are essential for virus release. We now show that the PPXY-type RSV L domain specifically recruits the BAR domain protein PACSIN2 into...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Popov, Sergei, Popova, Elena, Inoue, Michio, Wu, Yuanfei, Göttlinger, Heinrich
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2018
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142272/
https://ncbi.nlm.nih.gov/pubmed/29891700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1801849115
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