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Timing of DNA damage responses impacts persistence to fluoroquinolones

Bacterial persisters are subpopulations of phenotypic variants in isogenic cultures that can survive lethal doses of antibiotics. Their tolerances are often attributed to reduced activities of antibiotic targets, which limit corruption and damage in persisters compared with bacteria that die from tr...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Mok, Wendy W. K., Brynildsen, Mark P.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142227/
https://ncbi.nlm.nih.gov/pubmed/29915065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804218115
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