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The complex underpinnings of genetic background effects

Genetic interactions between mutations and standing polymorphisms can cause mutations to show distinct phenotypic effects in different individuals. To characterize the genetic architecture of these so-called background effects, we genotype 1411 wild-type and mutant yeast cross progeny and measure th...

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Udgivet i:Nat Commun
Main Authors: Mullis, Martin N., Matsui, Takeshi, Schell, Rachel, Foree, Ryan, Ehrenreich, Ian M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6141565/
https://ncbi.nlm.nih.gov/pubmed/30224702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06023-5
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