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Genetic suppression: Extending our knowledge from lab experiments to natural populations

Many mutations have deleterious phenotypic effects that can be alleviated by suppressor mutations elsewhere in the genome. High-throughput approaches have facilitated the large-scale identification of these suppressors and have helped shed light on core functional mechanisms that give rise to suppre...

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Библиографические подробности
Опубликовано в: :Bioessays
Главные авторы: Matsui, Takeshi, Lee, Jonathan T., Ehrenreich, Ian M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736388/
https://ncbi.nlm.nih.gov/pubmed/28471485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201700023
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