Oral nitrite restores age-dependent phenotypes in eNOS-null mice

Alterations in the synthesis and bioavailability of NO are central to the pathogenesis of cardiovascular and metabolic disorders. Although endothelial NO synthase–derived (eNOS-derived) NO affects mitochondrial long-chain fatty acid β-oxidation, the pathophysiological significance of this regulation...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Tenopoulou, Margarita, Doulias, Paschalis-Thomas, Nakamoto, Kent, Berrios, Kiara, Zura, Gabriella, Li, Chenxi, Faust, Michael, Yakovishina, Veronika, Evans, Perry, Tan, Lu, Bennett, Michael J., Snyder, Nathaniel W., Quinn, William J., Baur, Joseph A., Atochin, Dmitriy N., Huang, Paul L., Ischiropoulos, Harry
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6141175/
https://ncbi.nlm.nih.gov/pubmed/30135317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122156
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