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Strategies for Correcting Very Long Chain Acyl-CoA Dehydrogenase Deficiency

Very long acyl-CoA dehydrogenase (VLCAD) deficiency is a genetic pediatric disorder presenting with a spectrum of phenotypes that remains for the most part untreatable. Here, we present a novel strategy for the correction of VLCAD deficiency by increasing mutant VLCAD enzymatic activity. Treatment o...

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Vydáno v:J Biol Chem
Hlavní autoři: Tenopoulou, Margarita, Chen, Jie, Bastin, Jean, Bennett, Michael J., Ischiropoulos, Harry, Doulias, Paschalis-Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400356/
https://ncbi.nlm.nih.gov/pubmed/25737446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.635102
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