Pharmacokinetics of evocalcet in secondary hyperparathyroidism patients receiving hemodialysis: first-in-patient clinical trial in Japan

PURPOSE: Cinacalcet is a positive allosteric modulator of calcium-sensing receptors in the parathyroid gland and an effective treatment for secondary hyperparathyroidism. However, this agent has considerable side effects and dosage limitations, which impair effective treatment. Therefore, we investi...

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Vydáno v:Clin Pharmacol
Hlavní autoři: Shigematsu, Takashi, Shimazaki, Ryutaro, Fukagawa, Masafumi, Akizawa, Tadao
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2018
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6141109/
https://ncbi.nlm.nih.gov/pubmed/30254496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S171044
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