Rho Guanine Nucleotide Exchange Factor ARHGEF17 Is a Risk Gene for Intracranial Aneurysms

BACKGROUND: Intracranial Aneurysm (IA) is usually a late-onset disease, affecting 1-3% of the general population and leading to life-threatening subarachnoid hemorrhage (SAH). Genetic susceptibility has been implicated in IAs but the causative genes remain elusive. METHODS: We performed next-generat...

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Detalhes bibliográficos
Publicado no:Circ Genom Precis Med
Main Authors: Yang, Xinyu, Li, Jiani, Fang, Yabo, Zhang, Zhen, Jin, Daqing, Chen, Xingdong, Zhao, Yan, Li, Mengqi, Huan, Linchun, Kent, Thomas A., Dong, Jing-fei, Jiang, Rongcai, Yang, Shuyuan, Jin, Li, Zhang, Jianning, Zhong, Tao P., Yu, Fuli
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6141028/
https://ncbi.nlm.nih.gov/pubmed/29997225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGEN.117.002099
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