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Activation of Class I histone deacetylases contributes to mitochondrial dysfunction in cardiomyocytes with altered complex activities

Histone deacetylases (HDACs) play vital roles in the pathophysiology of heart failure, which is associated with mitochondrial dysfunction. Tumor necrosis factor-α (TNF-α) contributes to the genesis of heart failure and impairs mitochondria. This study evaluated the role of HDACs in TNF-α-induced mit...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Lkhagva, Baigalmaa, Kao, Yu-Hsun, Lee, Ting-I, Lee, Ting-Wei, Cheng, Wan-Li, Chen, Yi-Jen
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6140820/
https://ncbi.nlm.nih.gov/pubmed/29613828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2018.1460032
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