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Activation of Class I histone deacetylases contributes to mitochondrial dysfunction in cardiomyocytes with altered complex activities

Histone deacetylases (HDACs) play vital roles in the pathophysiology of heart failure, which is associated with mitochondrial dysfunction. Tumor necrosis factor-α (TNF-α) contributes to the genesis of heart failure and impairs mitochondria. This study evaluated the role of HDACs in TNF-α-induced mit...

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Bibliografiske detaljer
Udgivet i:Epigenetics
Main Authors: Lkhagva, Baigalmaa, Kao, Yu-Hsun, Lee, Ting-I, Lee, Ting-Wei, Cheng, Wan-Li, Chen, Yi-Jen
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6140820/
https://ncbi.nlm.nih.gov/pubmed/29613828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2018.1460032
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