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Meis1 is specifically upregulated in kidney myofibroblasts during aging and injury but is not required for kidney homeostasis or fibrotic response

The homeobox transcription factor Meis1 is required for mammalian development, and its overexpression plays a role in tumorigenesis, especially leukemia. Meis1 is known to be expressed in kidney stroma, but its function in kidney is undefined. We hypothesized that Meis1 may regulate stromal cell pro...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Chang-Panesso, Monica, Kadyrov, Farid F., Machado, Flavia G., Kumar, Ashish, Humphreys, Benjamin D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139520/
https://ncbi.nlm.nih.gov/pubmed/29592525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00030.2018
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