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Loss of biliverdin reductase-A promotes lipid accumulation and lipotoxicity in mouse proximal tubule cells

Obesity and increased lipid availability have been implicated in the development and progression of chronic kidney disease. One of the major sites of renal lipid accumulation is in the proximal tubule cells of the kidney, suggesting that these cells may be susceptible to lipotoxicity. We previously...

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Bibliografische gegevens
Gepubliceerd in:Am J Physiol Renal Physiol
Hoofdauteurs: Adeosun, Samuel O., Gordon, Darren M., Weeks, Mary Frances, Moore, Kyle H., Hall, John E., Hinds, Terry D., Stec, David E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139518/
https://ncbi.nlm.nih.gov/pubmed/29631357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00495.2017
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