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Targeting Checkpoint Receptors and Molecules for Therapeutic Modulation of Natural Killer Cells

Among the most promising therapeutic modalities for cancer treatment is the blockade of immune checkpoint pathways, which are frequently co-opted by tumors as a major mechanism of immune escape. CTLA-4 and PD-1 are the representative examples, and their blockade by therapeutic antibodies leads to en...

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Detaylı Bibliyografya
Yayımlandı:Front Immunol
Asıl Yazarlar: Kim, Nayoung, Kim, Hun Sik
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139314/
https://ncbi.nlm.nih.gov/pubmed/30250471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02041
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