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Targeting Checkpoint Receptors and Molecules for Therapeutic Modulation of Natural Killer Cells

Among the most promising therapeutic modalities for cancer treatment is the blockade of immune checkpoint pathways, which are frequently co-opted by tumors as a major mechanism of immune escape. CTLA-4 and PD-1 are the representative examples, and their blockade by therapeutic antibodies leads to en...

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Bibliografski detalji
Izdano u:Front Immunol
Glavni autori: Kim, Nayoung, Kim, Hun Sik
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139314/
https://ncbi.nlm.nih.gov/pubmed/30250471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02041
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