Susceptibility to Plasmodium vivax malaria associated with DARC (Duffy antigen) polymorphisms is influenced by the time of exposure to malaria

Malaria has provided a major selective pressure and has modulated the genetic diversity of the human genome. The variants of the Duffy Antigen/Receptor for Chemokines (DARC) gene have probably been selected by malaria parasites, particularly the FY*O allele, which is fixed in sub-Saharan Africa and...

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Foilsithe in:Sci Rep
Main Authors: Kano, Flora Satiko, de Souza, Aracele Maria, de Menezes Torres, Leticia, Costa, Marcelo Azevedo, Souza-Silva, Flávia Alessandra, Sanchez, Bruno Antônio Marinho, Fontes, Cor Jesus Fernandes, Soares, Irene Silva, de Brito, Cristiana Ferreira Alves, Carvalho, Luzia Helena, Sousa, Tais Nobrega
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2018
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138695/
https://ncbi.nlm.nih.gov/pubmed/30218021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32254-z
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