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SHLD2/FAM35A co‐operates with REV7 to coordinate DNA double‐strand break repair pathway choice
DNA double‐strand breaks (DSBs) can be repaired by two major pathways: non‐homologous end‐joining (NHEJ) and homologous recombination (HR). DNA repair pathway choice is governed by the opposing activities of 53BP1, in complex with its effectors RIF1 and REV7, and BRCA1. However, it remains unknown h...
Gorde:
| Argitaratua izan da: | EMBO J |
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| Egile Nagusiak: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
John Wiley and Sons Inc.
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6138439/ https://ncbi.nlm.nih.gov/pubmed/30154076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018100158 |
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