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Investigation of Protein Recruitment to DNA Lesions Using 405 Nm Laser Micro-irradiation

The DNA Damage Response (DDR) uses a plethora of proteins to detect, signal, and repair DNA lesions. Delineating this response is critical to understand genome maintenance mechanisms. Since recruitment and exchange of proteins at lesions are highly dynamic, their study requires the ability to genera...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Gaudreau-Lapierre, Antoine, Garneau, Daniel, Djerir, Billel, Coulombe, Frédéric, Morin, Théo, Marechal, Alexandre
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933222/
https://ncbi.nlm.nih.gov/pubmed/29630045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57410
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