Phenotypic differences between Drosophila Alzheimer’s disease models expressing human Aβ42 in the developing eye and brain

Drosophila melanogaster expressing amyloid-β42 (Aβ42) transgenes have been used as models to study Alzheimer’s disease. Various Aβ42 transgenes with different structures induce different phenotypes, which make it difficult to compare data among studies which use different transgenic lines. In this s...

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Veröffentlicht in:Anim Cells Syst (Seoul)
Hauptverfasser: Jeon, Youngjae, Lee, Soojin, Shin, Myoungchul, Lee, Jang Ho, Suh, Yoon Seok, Hwang, Soojin, Yun, Hye Sup, Cho, Kyoung Sang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2017
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138326/
https://ncbi.nlm.nih.gov/pubmed/30460065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19768354.2017.1313777
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