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Repeated immune activation with low-dose lipopolysaccharide attenuates the severity of Huntington's disease in R6/2 transgenic mice

Huntington's disease (HD) is a neurodegenerative disorder caused by a mutation in the huntingtin gene. Previously, therapeutic approaches using anti-inflammatory agents were reportedly not effective for preventing HD progression. Since whether immune responses contribute to the onset of HD is n...

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Detalhes bibliográficos
Publicado no:Anim Cells Syst (Seoul)
Main Authors: Lee, Sung Won, Park, Hyun Jung, Im, Wooseok, Kim, Manho, Hong, Seokmann
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138304/
https://ncbi.nlm.nih.gov/pubmed/30460101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19768354.2018.1473291
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