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GABA beyond the synapse: defining the subtype‐specific pharmacodynamics of non‐synaptic GABA(A) receptors

KEY POINTS: Physiologically relevant combinations of recombinant GABA(A) receptor (GABAR) subunits were expressed in HEK293 cells. Using whole‐cell voltage clamp and rapid drug application, we measured the GABAR‐subtype‐specific properties to convey either synaptic or extrasynaptic signalling in a r...

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Publicat a:J Physiol
Autors principals: Lagrange, Andre H., Hu, NingNing, Macdonald, Robert L.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138284/
https://ncbi.nlm.nih.gov/pubmed/30019335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP276187
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