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p53-Dependent Activation of the Mouse MCK Gene Promoter: Identification of a Novel p53-Responsive Sequence and Evidence for Cooperation Between Distinct p53 Binding Sites

Transcriptional activation by p53 is dependent on the presence of a specific p53 binding site within control sequences of the target gene. One such target gene is the mouse muscle-specific creatine kinase (MCK) gene, which contains a p53 binding site between promoter residues −3182 and −3133 relativ...

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Publicat a:Gene Expr
Autors principals: Jackson, Paul, Shield, Margaret, Buskin, Jean, Hawkes, Sheryl, Reed, Michael, Perrem, Kilian, Hauschka, Stephen D., Braithwaite, Antony
Format: Artigo
Idioma:Inglês
Publicat: Cognizant Communication Corporation 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138033/
https://ncbi.nlm.nih.gov/pubmed/7488858
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