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Sequential Steps in Tat Trans-Activation of HIV-1 Mediated Through Cellular DNA, RNA, and Protein Binding Factors

The regulation of HIV expression is controlled by the activity of the Long Terminal Repeat (LTR). Trans-activation by the virally encoded Tat protein is one of the main mechanisms of LTR activation. Tat binds to its target, TAR RNA, and cellular proteins that bind the LTR, Tat, or TAR RNA are import...

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Detalhes bibliográficos
Publicado no:Gene Expr
Main Authors: Gatignol, Anne, Duarte, Mariela, Daviet, Laurent, Chang, Yung-Nien, Jeang, Kuan-Teh
Formato: Artigo
Idioma:Inglês
Publicado em: Cognizant Communication Corporation 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138028/
https://ncbi.nlm.nih.gov/pubmed/8723388
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