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Functional Expression and Peroxisomal Targeting of Rat Urate Oxidase in Monkey Kidney Cells

Humans and hominoid primates lack the enzyme urate oxidase, which catalyzes the oxidation of uric acid to allantoin. In rats and most other mammals, urate oxidase is present as a crystalloid core within the peroxisomes of liver parenchymal cells. To determine whether functionally active recombinantl...

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Publicado en:Gene Expr
Autores principales: Yeldandi, Anjana V., Chu, Ruiyin, Reddy, Shweta K., Pan, Jie, Usuda, Nobuteru, Lin, Yulian, Rao, M. Sambasiva, Reddy, Janardan K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cognizant Communication Corporation 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138009/
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