Functional Expression and Peroxisomal Targeting of Rat Urate Oxidase in Monkey Kidney Cells

Humans and hominoid primates lack the enzyme urate oxidase, which catalyzes the oxidation of uric acid to allantoin. In rats and most other mammals, urate oxidase is present as a crystalloid core within the peroxisomes of liver parenchymal cells. To determine whether functionally active recombinantl...

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Veröffentlicht in:Gene Expr
Hauptverfasser: Yeldandi, Anjana V., Chu, Ruiyin, Reddy, Shweta K., Pan, Jie, Usuda, Nobuteru, Lin, Yulian, Rao, M. Sambasiva, Reddy, Janardan K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cognizant Communication Corporation 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138009/
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