3-Chloro-N′-(2-hydroxybenzylidene) benzohydrazide: An LSD1-Selective Inhibitor and Iron-Chelating Agent for Anticancer Therapy

Despite the discovery and development of novel therapies, cancer is still a leading cause of death worldwide. In order to grow, tumor cells require large quantities of nutrients involved in metabolic processes, and an increase in iron levels is known to contribute to cancer proliferation. Iron plays...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Sarno, Federica, Papulino, Chiara, Franci, Gianluigi, Andersen, Jeanette H., Cautain, Bastien, Melardo, Colombina, Altucci, Lucia, Nebbioso, Angela
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137965/
https://ncbi.nlm.nih.gov/pubmed/30245629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01006
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