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Triglycerides Promote Lipid Homeostasis during Hypoxic Stress by Balancing Fatty Acid Saturation

Lipid droplets, which store triglycerides and cholesterol esters, are a prominent feature of clear cell renal cell carcinoma (ccRCC). Although their presence in ccRCC is critical for sustained tumorigenesis, their contribution to lipid homeostasis and tumor cell viability is incompletely understood....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Rep
Hauptverfasser: Ackerman, Daniel, Tumanov, Sergey, Qiu, Bo, Michalopoulou, Evdokia, Spata, Michelle, Azzam, Andrew, Xie, Hong, Simon, M. Celeste, Kamphorst, Jurre J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137821/
https://ncbi.nlm.nih.gov/pubmed/30184495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.08.015
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