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Triglycerides Promote Lipid Homeostasis during Hypoxic Stress by Balancing Fatty Acid Saturation

Lipid droplets, which store triglycerides and cholesterol esters, are a prominent feature of clear cell renal cell carcinoma (ccRCC). Although their presence in ccRCC is critical for sustained tumorigenesis, their contribution to lipid homeostasis and tumor cell viability is incompletely understood....

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Ackerman, Daniel, Tumanov, Sergey, Qiu, Bo, Michalopoulou, Evdokia, Spata, Michelle, Azzam, Andrew, Xie, Hong, Simon, M. Celeste, Kamphorst, Jurre J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137821/
https://ncbi.nlm.nih.gov/pubmed/30184495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.08.015
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