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Muscarinic receptors 2 and 5 regulate bitter response of urethral brush cells via negative feedback

We have recently identified a cholinergic chemosensory cell in the urethral epithelium, urethral brush cell (UBC), that, upon stimulation with bitter or bacterial substances, initiates a reflex detrusor activation. Here, we elucidated cholinergic mechanisms that modulate UBC responsiveness. We analy...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:FASEB J
Hauptverfasser: Deckmann, Klaus, Rafiq, Amir, Erdmann, Christian, Illig, Christian, Durschnabel, Melanie, Wess, Jürgen, Weidner, Wolfgang, Bschleipfer, Thomas, Kummer, Wolfgang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137718/
https://ncbi.nlm.nih.gov/pubmed/29401598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700582R
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